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|Cartoon debut||"Francine and the Feline"|
Amoebas are a type of single-celled organism. They appeared in the opening of "Francine and the Feline" as Binky said that he always wanted one and heard that they were friendly. These amoebas are very friendly and said "Hey there! Hi! How's it going? Hello!" They never appeared again, this most likely means that Binky did not own them.